Document Detail

Changes in glycine content in mouse brain during hypoxic preconditioning.
MedLine Citation:
PMID:  11930226     Owner:  NLM     Status:  MEDLINE    
Glycine content of the whole brain and subregions was measured by high pressure liquid chromatography (HPLC) in mice during their repetitive exposures to hypoxia. The contents of glycine in whole brain, diencephalon, and hippocampus and brain stem was significantly increased as the animals tolerance to hypoxia was increased. The results suggest that glycine, as an inhibitory neurotransmitter in the brain, may positively contribute to the development of hypoxic preconditioning.
H Y Liu; G W Lu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Sheng li xue bao : [Acta physiologica Sinica]     Volume:  53     ISSN:  0371-0874     ISO Abbreviation:  Sheng Li Xue Bao     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2002-04-03     Completed Date:  2002-11-19     Revised Date:  2006-04-03    
Medline Journal Info:
Nlm Unique ID:  20730130R     Medline TA:  Sheng Li Xue Bao     Country:  China    
Other Details:
Languages:  eng     Pagination:  461-4     Citation Subset:  IM    
Department of Pharmacology, Bethune Medical University, Changchun 130021, China.
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MeSH Terms
Brain / metabolism*
Glycine / metabolism*
Hypoxia, Brain / metabolism*
Ischemic Preconditioning
Reg. No./Substance:

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