Document Detail

Changes in frequency of orthostatic hypotension in elderly hypertensive patients under medications.
MedLine Citation:
PMID:  8695026     Owner:  NLM     Status:  MEDLINE    
To evaluate changes in frequency of orthostatic blood pressure (BP) reduction (orthostatic hypotension; OH) in elderly hypertensive patients (HT) before and after treatment for hypertension, we measured BP after supine for 10 min and standing position for 2 min, before and after treatment for 2 years by five kinds of antihypertensive drugs in 50 elderly normotensive subjects (NT) and each of 50 HT in double-blind study. Orthostatic hypotension was defined as 10% or more decline of supine mean BP, and the frequency of OH was in 27% of HT following BP reduction by any kinds of antihypertensive drugs. In conclusion, the reducing or normalized BP by treatment for hypertension in elderly HT decreases the prevalence of orthostatic hypotension.
K Masuo; H Mikami; T Ogihara; M L Tuck
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of hypertension     Volume:  9     ISSN:  0895-7061     ISO Abbreviation:  Am. J. Hypertens.     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1996-08-30     Completed Date:  1996-08-30     Revised Date:  2009-02-24    
Medline Journal Info:
Nlm Unique ID:  8803676     Medline TA:  Am J Hypertens     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  263-8     Citation Subset:  IM    
Department of Geriatric Medicine, Osaka University Medical School, Japan.
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MeSH Terms
Antihypertensive Agents / therapeutic use*
Blood Pressure / drug effects
Double-Blind Method
Hypertension / blood,  drug therapy,  physiopathology*
Hypotension, Orthostatic / blood,  physiopathology*
Norepinephrine / blood
Reg. No./Substance:
0/Antihypertensive Agents; 51-41-2/Norepinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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