| Changes in the facility of aqueous outflow induced by lens depression and intraocular pressure in excised human eyes. | |
| | |
MedLine Citation:
|
PMID: 998694 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The effects of intraocular pressure on aqueous outflow facility and mechanical tension on the iridocorneal angle were evaluated in 44 excised postmortem human eyes. Mechanical tension on the iridocorneal angle was induced by depression of the crystalline lens posteriorly in a quantitative manner to simulate the effect of cyclotonia on the facility of aqueout outflow. In eyes perfused at constant intraocular pressure but with stepwise increases in lens depression, the increase in facility of outflow produced by the increased tension on the iridocorneal angle was minimal at low levels of intraocular pressure (2.5 and 5 mm Hg) and greatest at higher levels of intraocular pressure (10 to 25 mm Hg). Conversely, in pairs of eyes perfused over a graded series of increasing intraocular pressure, and subjected to maximal lens depression, facility of outflow remained constant until intraocular pressure exceeded 20 mm Hg; in the fellow eyes, perfused without lens depression, facility of outflow diminished linearly with increasing intraocular pressure. |
| | |
Authors:
|
E M Van Buskirk |
Related Documents
:
|
1702244 - Hypertension and myocarditis in rabbits exposed to hexachlorocyclohexane and endosulfan. 6178094 - Substance p in tumors: pheochromocytoma and carcinoid. 3184554 - Ocular hypotensive effects of monoamine oxidase-a inhibitors in rabbit. 7239844 - Constant-area applanation tonography. 7350844 - Surgery in oculopharyngeal muscular dystrophy. 9383184 - Clinical results of the verapamil inhypertension and atherosclerosis study. vhas invest... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: American journal of ophthalmology Volume: 82 ISSN: 0002-9394 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 1976 Nov |
Date Detail:
|
Created Date: 1977-01-25 Completed Date: 1977-01-25 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 736-40 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aqueous Humor / physiology* Glaucoma / physiopathology Humans Intraocular Pressure* Lens, Crystalline / physiopathology* Organ Culture Techniques Perfusion Stress, Mechanical |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A histologic survey of trabeculectomy.
Next Document: Ocular enucleation in a patient with severe classic hemophilia A.