| Changes in the expression of prekeratins with molecular weight of 55 and 40 kD in monolayer epithelium during skin morphogenesis in rats | |
| | |
MedLine Citation:
|
PMID: 2436683 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
It has been shown by indirect immunofluorescence using monoclonal antibodies against adult rat simple epithelial prekeratins with the molecular weight of 55 kD (PK55) and 40 kD (PK40) that PK55 was expressed in the covering ectoderm until the 11th day of the antenatal period. PK55 expression markedly increased in ectodermal cells lining the heart region, with PK40 appearing in the same cells on day 11. Beginning from the 16th day gradual loss of both prekeratins started with the parallel formation of squamous differentiated epidermis. These proteins were retained in the outer layers of peridermal cells and in some cells of the basal layer (probably Merkel cells). PK55 was re-expressed on the 18th day in cells migrating into dermal layer during hair folliculi formation. PK55 disappeared again in mature folliculi. Thus, a correlation between distinct morphogenetic events and PK55 and PK40 expression has been found. |
| | |
Authors:
|
S M Troianovskiĭ; A S Gleĭberman; G A Bannikov |
Publication Detail:
|
Type: English Abstract; Journal Article |
Journal Detail:
|
Title: Biulleten' eksperimental'noĭ biologii i meditsiny Volume: 103 ISSN: 0365-9615 ISO Abbreviation: Biull Eksp Biol Med Publication Date: 1987 Apr |
Date Detail:
|
Created Date: 1987-06-17 Completed Date: 1987-06-17 Revised Date: 2008-10-08 |
Medline Journal Info:
|
Nlm Unique ID: 0370627 Medline TA: Biull Eksp Biol Med Country: USSR |
Other Details:
|
Languages: rus Pagination: 478-81 Citation Subset: IM |
Vernacular Title:
|
Izmeneniia ékspressii prekeratinov odnosloĭnogo épiteliia s mol. massami 55 i 40 kD pri morfogeneze kozhi krys. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Epithelium / embryology Female Keratins / analysis* Male Molecular Weight Morphogenesis Protein Precursors / analysis* Rats Rats, Inbred F344 Skin / embryology* |
| Chemical | |
Reg. No./Substance:
|
0/Protein Precursors; 0/prekeratin; 68238-35-7/Keratins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Inhibition of alpha-fetoprotein synthesis in hepatocytes of adult mice by dextran sulfate in vivo an...
Next Document: The pathogenesis of accelerated fibrinolysis in liver cirrhosis: a critical role for tissue plasmino...