| Changes in endochondral bone elongation rates during pregnancy and lactation in rats. | |
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MedLine Citation:
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PMID: 6442205 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The rates of endochondral bone elongation during pregnancy and lactation in rats have been studied. The rate of growth at the distal femoral epiphyseal growth plate was measured using fluorescent bone markers. Endochondral growth rates were substantially increased in pregnant animals when compared with age-matched, nonmated controls. There were also increases in growth plate thickness, hypertrophic cell lacunar height, and the calculated rate of cell production during pregnancy. At parturition, this growth trend was reversed and during lactation there were significant decreases in endochondral growth rates. There were also corresponding decreases in growth plate thickness, hypertrophic cell lacunar height, and the calculated rate of cartilage cell production. These results indicate that significant changes occur in maternal endochondral growth rates during the reproductive cycle in rats. |
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Authors:
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E H Redd; S C Miller; W S Jee |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Calcified tissue international Volume: 36 ISSN: 0171-967X ISO Abbreviation: Calcif. Tissue Int. Publication Date: 1984 Dec |
Date Detail:
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Created Date: 1985-05-10 Completed Date: 1985-05-10 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7905481 Medline TA: Calcif Tissue Int Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 697-701 Citation Subset: IM; S |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bone Development* Female Femur / growth & development Growth Plate / anatomy & histology* Lactation* Pregnancy Rats Rats, Inbred Strains Tibia / growth & development |
| Grant Support | |
ID/Acronym/Agency:
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DE-06007/DE/NIDCR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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