Document Detail

Changes in depressive symptoms after continuous positive airway pressure treatment for obstructive sleep apnea.
MedLine Citation:
PMID:  12712395     Owner:  NLM     Status:  MEDLINE    
It is generally believed that obstructive sleep apnea (OSA) causes depression in some patients, yet it is unknown whether this depression is an actual clinical phenomenon or purely a result of overlapping somatic/physical symptoms shared by both disorders. The present study investigated changes in both somatic and affective/cognitive symptoms of depression associated with the introduction of continuous positive airway pressure (CPAP) treatment for OSA. Participants were 39 outpatients (35 males, 4 females) with no current or past mental health problems, diagnosed with OSA in a hospital sleep disorders clinic. The Beck Depression Inventory (BDI) was administered prior to treatment and again 3 months after CPAP. Total BDI scores improved after CPAP, independent of objectively monitored CPAP compliance rates. Both somatic and affective/ cognitive symptoms of depression improved in a similar manner after treatment. Our findings suggest that depressive symptoms experienced by OSA patients are not solely the result of physical OSA symptoms but include a mood component as well. We introduce a hypothetical model to conceptualize the relationship between OSA and depression.
Melanie K Means; Kenneth L Lichstein; Jack D Edinger; Daniel J Taylor; H Heith Durrence; Aatif M Husain; R Neal Aguillard; Rodney A Radtke
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Sleep & breathing = Schlaf & Atmung     Volume:  7     ISSN:  1520-9512     ISO Abbreviation:  Sleep Breath     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-04-24     Completed Date:  2003-08-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9804161     Medline TA:  Sleep Breath     Country:  United States    
Other Details:
Languages:  eng     Pagination:  31-42     Citation Subset:  IM    
Psychology Service, Department of Veterans Affairs Medical Center, Durham, North Carolina 27705, USA.
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MeSH Terms
Body Mass Index
Depression / diagnosis*,  epidemiology,  etiology*,  psychology
Disorders of Excessive Somnolence / epidemiology
Positive-Pressure Respiration / methods*
Severity of Illness Index
Sleep Apnea, Obstructive / epidemiology,  psychology*,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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