Document Detail

Changes in corneal thickness and curvature after different excimer laser photorefractive procedures and their impact on intraocular pressure measurements.
MedLine Citation:
PMID:  16003513     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Excimer laser refractive surgery alters the shape and thickness of the cornea by removing central corneal tissue with submicrometer precision. The aim of the study was to analyze the changes in central corneal thickness (CCT) and curvature before and after different excimer laser photorefractive procedures and their possible impact on intraocular pressure (IOP) estimations with Goldmann applanation tonometry. METHODS: Data on CCT, corneal curvature and IOP readings with Goldmann applanation tonometry before and after excimer laser photorefractive surgery were analyzed retrospectively. The data was further analyzed separately in two subgroups; the photorefractive keratectomy /laser-assisted subepithelial keratomileusis (PRK/LASEK) group and the laser in situ keratomileusis (LASIK) group. RESULTS: The overall post-operative IOP readings were significantly lower than pre-operative values. There was a significant difference in the lowering of the IOP readings between the two subgroups: LASIK caused a lower IOP reading than PRK/LASEK. CONCLUSION: The change in corneal thickness and curvature affects the estimation of IOP with Goldmann applanation tonometry after excimer laser photorefractive surgery. The amount of reduction in IOP reading might be influenced by the specific laser surgical procedure. This is of clinical importance in the evaluation of any future glaucoma in the increasing number of patients who undergo photorefractive laser surgery.
Helena Svedberg; Enping Chen; Helene Hamberg-Nyström
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-07-08
Journal Detail:
Title:  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie     Volume:  243     ISSN:  0721-832X     ISO Abbreviation:  Graefes Arch. Clin. Exp. Ophthalmol.     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-11-29     Completed Date:  2006-05-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8205248     Medline TA:  Graefes Arch Clin Exp Ophthalmol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1218-20     Citation Subset:  IM    
St Erik's Eye Hospital, Karolinska Institutet, Stockholm, Sweden.
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MeSH Terms
Cornea / pathology*,  surgery
Corneal Surgery, Laser*
Follow-Up Studies
Intraocular Pressure / physiology*
Refractive Errors / pathology,  physiopathology
Refractive Surgical Procedures*
Retrospective Studies
Tonometry, Ocular / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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