| Changes in the connective tissue composition of the submucosal layer of colonic anastomosis. An immunohistologic study in rats. | |
| | |
MedLine Citation:
|
PMID: 2596249 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Submucosal healing of colonic anastomosis was studied in rats. The unprepared sigmoid colon was divided and colo-colostomy performed, using a one-layer inverting technique. Frozen sections were studied immunohistologically with specific antibodies to fibronectin, laminin and collagen types I, III, IV and V. From the first to the fifth postoperative day the submucosa was highly oedematous. A clear fibronectin reaction was observed in the submucosa, reaching maximum on postoperative day 5. From day 3 onwards the fluorescence intensities of types I and III collagen in the young granulation tissue and of types IV and V collagen and laminin in the regenerating capillaries rapidly increased, with maximum on day 7. The striking changes in the submucosa indicate that the healing process involves not only the actual area of the anastomosis, but also widely the submucosal layer of the adjacent intestine. |
| | |
Authors:
|
P Brasken; M Lehto; S Renvall |
Related Documents
:
|
15761979 - Protective effect of radix acanthopanacis senticosi capsule on colon of rat depression ... 20537799 - In vitro ovicidal activity of the nematophagous fungi duddingtonia flagrans, monacrospo... 10574109 - Influence of growth factors erythropoietin and granulocyte macrophage colony stimulatin... 15162549 - Effects of mu and kappa opioid receptor agonists and antagonists on contraction of isol... 2323159 - Electrolyte transport in rat colon: comparative effects of intestinal resections and by... 17164549 - Effects of simultaneous hepatic resection on healing of left-sided colonic anastomoses:... 7906889 - Chronic administration of an alpha 2 adrenergic agonist desensitizes rats to the anesth... 8400919 - Prostaglandin e2 increased rat cortical bone mass when administered immediately followi... 12697399 - Intracerebroventricular calcitonin prevents stress-induced gastric dysfunction. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Acta chirurgica Scandinavica Volume: 155 ISSN: 0001-5482 ISO Abbreviation: Acta Chir Scand Publication Date: 1989 Aug |
Date Detail:
|
Created Date: 1990-01-23 Completed Date: 1990-01-23 Revised Date: 2003-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 7906530 Medline TA: Acta Chir Scand Country: SWEDEN |
Other Details:
|
Languages: eng Pagination: 413-9 Citation Subset: IM |
Affiliation:
|
Department of Surgery, University of Turku, Finland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anastomosis, Surgical* Animals Collagen / physiology* Colon / surgery* Female Immunohistochemistry Intestinal Mucosa / cytology, physiology* Microscopy, Fluorescence Rats Rats, Inbred Strains Wound Healing |
| Chemical | |
Reg. No./Substance:
|
9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Jejunoileal bypass for morbid obesity. Report of a series with long-term results.
Next Document: Choledochoduodenal fistula: a rare complication of duodenal ulcer. Case report.