Document Detail

Changes in the concentration of monocytic chemotaxic protein-1 in patients with unstable angina treated with arixtra.
MedLine Citation:
PMID:  22235409     Owner:  NLM     Status:  In-Data-Review    
The time course of inflammatory reaction markers in the blood of patients with unstable angina was studied during therapy including arixtra. Plasma concentration of monocytic chemotaxic protein-1 (MCP-1) decreased on days 2 and 3 in patients receiving arixtra and a trend to an increase in MCP-1 concentration was observed on day 7 after the drug was discontinued. After 1 month, MCP-1 level decreased in all patients. The concentration of highly sensitive C-reactive protein also decreased 1 month after the disease onset; no changes in the concentrations of IL-8 and IL-2 receptor α-subunit were detected during these periods. It seems that arixtra is characterized by an anti-inflammatory effect manifesting by reduction of plasma chemokine MCP-1 concentration.
A V Potekhina; T I Arefieva; T L Krasnikova; S I Provatorov; V P Masenko; M K Osyaeva; E A Noeva
Related Documents :
10386299 - Metabolic responses of dairy cows and heifers to various intravenous dosages of glucagon.
22764539 - Toxicokinetics and correlation of carbamazepine salivary and serum concentrations in ac...
558549 - The effect of a peripheral decarboxylase inhibitor (carbidopa) on monoamine and neuroen...
956399 - Heterogeneity of plasma glucagon. circulating components in normal subjects and patient...
21978129 - Increased plasma levels of total homocysteine but not asymmetric dimethylarginine in hi...
7689499 - On the effects of human galanin in man.
3950529 - Urine ph and the relationship between urine flow and urinary prostaglandin e excretion ...
20651469 - Growth hormone secretion among adult patients with prader-willi syndrome due to differe...
16188899 - Use of cardiac troponin t in diagnosis and prognosis of cardiac events in patients on c...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  150     ISSN:  1573-8221     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2012-01-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng; rus     Pagination:  656-8     Citation Subset:  IM    
Russian Research and Practical Centre of Cardiology, Moscow, Russia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Changes in Systolic and Diastolic Functions of the Left Ventricle and Endothelium Function against t...
Next Document:  Morphofuctional aspects of antitumor activity of low-intensity microwave resonance radiation in expe...