Document Detail

Changes in concentration of human atrial natriuretic peptide in normal pregnancy and toxaemia.
MedLine Citation:
PMID:  2958577     Owner:  NLM     Status:  MEDLINE    
Changes in concentration of human atrial natriuretic peptide (hANP) in normal and toxaemic pregnancy were examined. The maternal plasma concentration of hANP increased gradually during normal pregnancy to a maximum of 20.0 +/- 2.4 pmol/l (mean +/- S.E.M.) after week 36 of pregnancy. From week 20, the plasma concentrations of hANP were significantly higher than those in non-pregnant women (9.3 +/- 2.0 pmol/l). In toxaemia with hypertension, maternal plasma hANP levels were increased after week 26 of pregnancy (37.7 +/- 6.0 pmol/l) compared with those in normal gravida at the same time (17.1 +/- 1.6 pmol/l). Maternal plasma hANP levels in toxaemia only with oedema were not different from those in normal gravida.
Y Otsuki; E Okamoto; I Iwata; E Nishino; N Mitsuda; M Mori; T Takagi; N Sugita; O Tanizawa
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of endocrinology     Volume:  114     ISSN:  0022-0795     ISO Abbreviation:  J. Endocrinol.     Publication Date:  1987 Aug 
Date Detail:
Created Date:  1987-10-29     Completed Date:  1987-10-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375363     Medline TA:  J Endocrinol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  325-8     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Osaka University Medical School, Japan.
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MeSH Terms
Atrial Natriuretic Factor / blood*
Edema / blood
Hypertension / blood
Pre-Eclampsia / blood*
Pregnancy / blood*
Reg. No./Substance:
85637-73-6/Atrial Natriuretic Factor

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