Document Detail

Changes in cerebral hemodynamics and cerebral oxygenation during surgical evacuation for hypertensive intracerebral putaminal hemorrhage.
MedLine Citation:
PMID:  16463829     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: The aim of this study was to evaluate the changes in cerebral hemodynamics, tissue oxygenation and blood flow before and after surgery for spontaneous intracerebral hematomas. METHODS: Eleven patients who underwent surgical decompression of spontaneous putaminal hematoma were studied. Intracranial pressure (ICP), cerebral perfusion pressure (CPP), brain tissue oxygen (PtiO2), and carbon dioxide tensions (PtiCO2), brain pH and regional cerebral blood flow (rCBF) were recorded prior to removing the bone flap and then on skin closure on completion of the operation. RESULTS: Following surgical decompression, mean ICP decreased significantly (P < 0.05); mean CPP, PtiO2, brain pH and rCBF improved although the changes were not significant. CONCLUSION: Surgical decompression for spontaneous intracerebral hematomas leads to significant reductions in ICP. This is accompanied by improvements in CPP, PtiO2 and rCBF in the penumbra.
I Ng; E Yap; J Lim
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta neurochirurgica. Supplement     Volume:  95     ISSN:  0065-1419     ISO Abbreviation:  Acta Neurochir. Suppl.     Publication Date:  2005  
Date Detail:
Created Date:  2006-02-08     Completed Date:  2006-03-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100962752     Medline TA:  Acta Neurochir Suppl     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  97-101     Citation Subset:  IM    
Department of Neurosurgery, National Neuroscience Institute, Singapore.
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MeSH Terms
Aged, 80 and over
Brain / blood supply,  metabolism,  surgery
Decompression, Surgical
Intracranial Hemorrhage, Hypertensive / complications,  physiopathology*,  surgery*
Intracranial Pressure*
Middle Aged
Oxygen / metabolism*
Putaminal Hemorrhage / complications,  physiopathology*,  surgery*
Treatment Outcome
Reg. No./Substance:

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