Document Detail

Changes in care and short-term outcome for very preterm infants in Estonia.
MedLine Citation:
PMID:  22150584     Owner:  NLM     Status:  Publisher    
Aim:  To identify recent changes in short-term outcome and care for very preterm infants in Estonia. Methods:  Comparison of two population-based cohorts of very preterm infants born alive at 22-31 gestational weeks. In 2007-2008, data were recorded prospectively in a neonatal register. For the cohort born in 2002-2003, the same variables were extracted retrospectively from the hospital records. Infants were followed up to discharge or death. Results:  The cohort of 2007-2008 contained a higher proportion of infants born by caesarean section, and of infants who received antenatal corticosteroids, maternal antibiotics, or surfactant therapy than the earlier cohort. A higher proportion of infants was admitted for care in 2007-2008 (98% vs 94%; p = 0.013). During the study period, survival until discharge increased (85% vs 78%; p = 0.041), although the length of hospital stay was unchanged. The use of mechanical ventilation, inotropes, and postnatal antibiotics decreased. Neonatal morbidity remained unchanged, except for a decrease in severe periventricular/intraventricular haemorrhage. Conclusion:  The outcome for very preterm infants in Estonia has improved since 2002. With proactive perinatal management and less invasive neonatal care, survival until discharge increased without concomitant increases in neonatal morbidity and the length of hospital stay.
L Toome; I Ringmets; P Andresson; M-L Ilmoja; P Saik; H Varendi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-9
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Acta Paediatrica © 2011 Foundation Acta Paediatrica.
Department of Paediatrics, University of Tartu, Tartu, Estonia Clinic of Paediatrics, Tallinn Children's Hospital, Tallinn, Estonia Department of Public Health, University of Tartu, Tartu, Estonia Women's Clinic, East-Tallinn Central Hospital, Tallinn, Estonia Women's Clinic, West-Tallinn Central Hospital, Tallinn, Estonia Children's Clinic, Tartu University Hospital, Tartu, Estonia.
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