Document Detail

Changes in cardiac functional capacity after coronary bypass surgery in relation to adequacy of revascularization.
MedLine Citation:
PMID:  6140278     Owner:  NLM     Status:  MEDLINE    
Seventy patients having aortocoronary vein bypass grafting surgery for angina pectoris underwent preoperative invasive exercise testing to symptom limits and again 6 to 14 months postoperatively. Cardiac output was measured using the direct Fick principle. Postoperatively at maximal exercise, there was a 3.11 liters/min (p less than 0.0001) increase in cardiac output in men (n = 61) and a 2.04 liters/min (p less than 0.01) increase in women (n = 9). Patients with complete revascularization showed a significantly greater improvement in cardiac output postoperatively than did those with incomplete revascularization (26 versus 6%, p less than 0.0001). The major reason for the increased maximal cardiac output was a marked increase in heart rate while stroke volume was maintained at the same preoperative level. These findings were true irrespective of preoperative use of beta-adrenergic blocking drugs.
K F Hossack; R A Bruce; T D Ivey; F Kusumi
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  3     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  1984 Jan 
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  47-54     Citation Subset:  IM    
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MeSH Terms
Adrenergic beta-Antagonists / administration & dosage
Angina Pectoris / surgery
Cardiac Output
Coronary Artery Bypass*
Exercise Test
Follow-Up Studies
Heart / physiology*
Heart Rate
Middle Aged
Oxygen / blood
Oxygen Consumption
Stroke Volume
Grant Support
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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