Document Detail

Changes in body composition and its relation to muscle strength in 75-year-old men and women: a 5-year prospective follow-up study of the NORA cohort in Göteborg, Sweden.
MedLine Citation:
PMID:  19211225     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to explore the association between body composition in the elderly and subsequent changes in muscle strength during aging. METHODS: This was a longitudinal study with a 5-y follow-up. Eighty-seven men (n = 38) and women (n = 49) from a random sample of 75-y-old subjects in the Göteborg part of the Nordic Research on Aging study who were investigated at ages 75 and 80 y and were free from any major diseases at baseline were included. Body composition was estimated from bioelectrical impedance. The maximal isometric strengths of handgrip, arm flexion, and knee extension were measured on the side of the dominant hand while a subject was in a sitting position in an adjustable dynamometer chair. RESULTS: Fat-free mass decreased significantly (P < 0.001) in both sexes, but more in men. Percentage of body fat increased only in men (P < 0.05). Body height decreased in both sexes, but more in women (P < 0.001). Declines in muscle strengths were evident for all muscle groups in both sexes but more prominent in men. It was observed that body composition status at baseline, measured as fat-free mass and fat-free mass index, was a statistically significant predictor for decline in muscle strength, particularly in the extremities. CONCLUSION: Fat-free mass at age 75 y was associated with lower 5-y decline in muscle strength. This finding underscores the potential importance of fat-free mass for maintaining functional ability during aging.
Debashish K Dey; Ingvar Bosaeus; Lauren Lissner; Bertil Steen
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Publication Detail:
Type:  Journal Article     Date:  2009-02-10
Journal Detail:
Title:  Nutrition (Burbank, Los Angeles County, Calif.)     Volume:  25     ISSN:  1873-1244     ISO Abbreviation:  Nutrition     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-05-01     Completed Date:  2009-06-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8802712     Medline TA:  Nutrition     Country:  United States    
Other Details:
Languages:  eng     Pagination:  613-9     Citation Subset:  IM    
Department of Geriatric Medicine, School of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
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MeSH Terms
Adipose Tissue / metabolism
Aged, 80 and over
Aging / physiology*
Body Composition / physiology*
Body Height / physiology
Body Weight / physiology
Cohort Studies
Electric Impedance
Follow-Up Studies
Hand Strength / physiology*
Longitudinal Studies
Muscle, Skeletal / metabolism,  physiology*
Prospective Studies
Sex Characteristics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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