| Changes in blood parameters in pregnant Japanese White rabbits. | |
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MedLine Citation:
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PMID: 20930472 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Changes in blood parameters, especially those related to blood coagulations, were examined on gestational days (GDs) 6, 18 and 28 in Japanese White rabbits. As compared with the non-pregnant group, the following changes were observed in the pregnant group. For blood coagulation-related parameters, fibrinogen, platelets and antithrombin time III (ATIII) was significantly increased on GD 18 and/or GD 28, and activated partial thromboplastin time (APTT) was significantly prolonged on GDs 18 and 28. For the other hematological and blood chemical parameters, hemoglobin and hematocrit values were significantly decreased on GDs 18 and 28. Reticulocyte counts significantly and prominently increased on GD 18 and then decreased to significantly lower levels than those in the non-pregnant group on GD 28. Eosinophils and basophil showed significant decreases on GD 18 and/or GD 28. The serum progesterone concentration reached its highest level on GD 18. Total protein (TP), albumin, alkaline phosphatase (ALP), alanine aminotransferase (ALT), cholesterol, calcium, glucose and blood urea nitrogen were significantly decreased on GD 18 and/or GD 28. These results were almost similar to those in the pregnant New Zealand White rabbits (Mizoguchi et al., 2010). |
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Authors:
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Ryo Haneda; Yasumoto Mizoguchi; Tetsuya Matsuoka; Hiroyasu Mizuguchi; Takako Endoh; Kazuya Fukuda; Yuzo Asano |
Publication Detail:
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Type: Letter |
Journal Detail:
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Title: The Journal of toxicological sciences Volume: 35 ISSN: 1880-3989 ISO Abbreviation: J Toxicol Sci Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-08 Completed Date: 2011-02-18 Revised Date: 2011-07-21 |
Medline Journal Info:
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Nlm Unique ID: 7805798 Medline TA: J Toxicol Sci Country: Japan |
Other Details:
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Languages: eng Pagination: 773-8 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Cell Count Blood Chemical Analysis Blood Coagulation* Blood Coagulation Tests Female Gestational Age Pregnancy Pregnancy, Animal / blood* Rabbits / blood* |
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