| Changes in Uroflowmetry Maximum Flow Rates After Urethral Reconstructive Surgery as a Means to Predict for Stricture Recurrence. | |
| | |
MedLine Citation:
|
PMID: 21944128 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
PURPOSE: A reliable, noninvasive screening method for urethral stricture recurrence after urethroplasty is needed. We hypothesized that changes in flow rates on uroflowmetry relative to preoperative values might help predict stricture recurrence. MATERIALS AND METHODS: All men who underwent urethral reconstructive surgery from 2000 to 2009 with adequate preoperative and postoperative uroflowmetry studies were included in the study. Preoperative and postoperative maximum flow rates were compared. The absolute change in maximum flow rate was compared between patients with and those without recurrence as determined by retrograde urethrogram. RESULTS: A total of 125 patients treated with urethroplasty were included in the study. Mean ± SD preoperative maximum flow rate was 11.8 ± 9.1 ml per second, which did not vary by stricture length (p = 0.11), patient age (p = 0.46) or stricture location (p = 0.58). The change in maximum flow rate in men without recurrence was 19.2 ± 11.7 vs 0.2 ± 6.4 ml per second (p <0.001) in failed repairs. Setting a change in maximum flow rate of less than 10 ml per second as a screen for stricture recurrence would have resulted in a test sensitivity and specificity of 92% and 78%, respectively. There were 85 men without stricture recurrence who underwent more than 1 postoperative uroflowmetry study. Repeated maximum flow rate values achieved reasonable test reproducibility (r = 0.52), further supporting the use of uroflowmetry. CONCLUSIONS: Change in flow rate after urethral reconstruction represents a promising metric to screen for stricture recurrence that is noninvasive and has a high sensitivity. |
| | |
Authors:
|
Bradley A Erickson; Benjamin N Breyer; Jack W McAninch |
Related Documents
:
|
8257978 - Respiratory measurements of occupational exposure to industrial solvents. 22171658 - A new screening technique for salinity resistance in rice (oryza sativa l.) seedlings u... 3128338 - Effect of distal endotracheal bias flow on paco2 during high frequency oscillatory vent... 9382938 - Pulmonary blood volume and its effects on pressure/flow relations and flow resistance i... 2607738 - Determination of blood volume in dogs using an enriched stable isotope 50cr. 6484008 - Mercury concentration in the blood and organs of normal and acatalasemic mice after int... |
Publication Detail:
|
Type: - Date: 2011-9-22 |
Journal Detail:
|
Title: The Journal of urology Volume: - ISSN: 1527-3792 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
|
Created Date: 2011-9-27 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0376374 Medline TA: J Urol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Urology, University of California, San Francisco, San Francisco, California. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Holmium Laser Enucleation of the Prostate: Long-Term Durability of Clinical Outcomes and Complicatio...
Next Document: Role of Inflammatory Related Gene Expression in Clear Cell Renal Cell Carcinoma Development and Clin...