| Changes in Treatment Adherence and Glycemic Control During the Transition to Adolescence in Type 1 Diabetes. | |
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MedLine Citation:
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PMID: 22474040 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVETo test models of unidirectional and bidirectional change between treatment adherence and glycemic control in youth with type 1 diabetes.RESEARCH DESIGN AND METHODSWe conducted a 2-year longitudinal, multisite study of 225 youth with type 1 diabetes recruited at the cusp of adolescence (aged 9-11 years) to describe the mutual influences of glycemic control as measured by HbA(1c) and treatment adherence as measured by blood glucose monitoring frequency (BGMF) during the transition to adolescence.RESULTSHbA(1c) increased from 8.2 to 8.6% (P < 0.001) and BGMF decreased from 4.9 to 4.5 checks per day (P < 0.02) during the 2-year period. Changes in the BGMF slope predicted changes in HbA(1c). A change (increase) in HbA(1c) was associated with a change (decrease) in BGMF of 1.26 (P < 0.001) after controlling for covariates.CONCLUSIONSThe magnitude of the effect of declining treatment adherence (BGMF) on glycemic control in young adolescents may be even greater than declines observed among older adolescents. BGMF offers a powerful tool for targeted management of glycemic control for type 1 diabetes during the critical transition to adolescence. |
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Authors:
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Joseph R Rausch; Korey K Hood; Alan Delamater; Jennifer Shroff Pendley; Jennifer M Rohan; Grafton Reeves; Lawrence Dolan; Dennis Drotar |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-4-3 |
Journal Detail:
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Title: Diabetes care Volume: - ISSN: 1935-5548 ISO Abbreviation: - Publication Date: 2012 Apr |
Date Detail:
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Created Date: 2012-4-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7805975 Medline TA: Diabetes Care Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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