| Changes of glycolipids dependent on cell density of Ehrlich ascites carcinoma cells. | |
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MedLine Citation:
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PMID: 6745256 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The glycolipid composition of Ehrlich ascites carcinoma cells was found to depend strongly on the cell density of the suspension. The general trend observed upon dilution of the cell suspension was a reduction of the less complex gangliosides GM3 and GM2 with concomitant increase of the more complex gangliosides, especially GM1. The increase of the content of ganglioside GM1 upon dilution was accompanied by a comparable decrease of the content of its immediate precursor, asialo-GM1, whereas the content of other neutral glycosphingolipids did not change very much. When the cell suspension was diluted with medium conditioned by dense cells the ganglioside profile of the diluted suspension remained similar to that of the dense cell suspension. It is postulated that the medium conditioned with dense cells contains a transferable factor inhibiting sialylation of asialo-GM1. |
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Authors:
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N V Prokazova; S L Kocharov; G I Shaposhnikova; N D Zvezdina; L D Bergelson |
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Publication Detail:
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Type: In Vitro; Journal Article |
Journal Detail:
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Title: European journal of biochemistry / FEBS Volume: 141 ISSN: 0014-2956 ISO Abbreviation: Eur. J. Biochem. Publication Date: 1984 Jun |
Date Detail:
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Created Date: 1984-09-05 Completed Date: 1984-09-05 Revised Date: 2007-07-23 |
Medline Journal Info:
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Nlm Unique ID: 0107600 Medline TA: Eur J Biochem Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 527-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Carcinoma, Ehrlich Tumor / metabolism*, pathology Cell Count Gangliosides / metabolism Glycolipids / metabolism* Glycosphingolipids / metabolism Male Mice |
| Chemical | |
Reg. No./Substance:
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0/Gangliosides; 0/Glycolipids; 0/Glycosphingolipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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