Document Detail

Changes on craniofacial structures in children with growth-hormone-deficiency.
MedLine Citation:
PMID:  21184713     Owner:  NLM     Status:  In-Process    
OBJECTIVE: To describe the growth of craniofacial structures in growth-hormone deficiency (GHD) children during growth-hormone therapy (GHT).
METHODS: A cross-sectional sample of 46 subjects (n = 14 girls, 32 boys) aged 4-18 years was obtained. They were categorized into two paired groups: the reference group, for comparing the cephalograms, consisted in 23 healthy subjects, and the study group (23 patients) with GHD under GHT. Differences between groups were assessed by independent t-tests.
RESULTS: The boys showed smaller measurements for all facial structures presenting significant differences in total mandibular length (Co-Pg p < 0.03), lower anterior facial height (ANS-Me p < 0.03) and total anterior facial height (N-Me p < 0.02) as well as retrognathic facial type. In girls the posterior cranial base length was shortened (S-Ba 29.14 ± 3.02 mm) and show a high mandibular plane angle (40 ± 5.50°) a wide relation anterior maxillo-mandibular (5.86 ± 1.57°) with a statistical difference (p < 0.05 and p < 0.04) compared with the reference group.
CONCLUSIONS: We suggest considering the cephalometric morphology at the beginning of GHT.
Ricardo Salas-Flores; Brian González-Pérez; Ricardo Leopoldo Barajas-Campos; Betzabe Gonzalez-Cruz
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Revista médica del Instituto Mexicano del Seguro Social     Volume:  48     ISSN:  0443-5117     ISO Abbreviation:  Rev Med Inst Mex Seguro Soc     Publication Date:    2010 Nov-Dec
Date Detail:
Created Date:  2010-12-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101243727     Medline TA:  Rev Med Inst Mex Seguro Soc     Country:  Mexico    
Other Details:
Languages:  eng     Pagination:  591-5     Citation Subset:  IM    
Hospital General Regional 6, Instituto Mexicano del Seguro Social, Ciudad. Tampico, Tamaulipas, México.
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