Document Detail

Changes of cortical motor area size during immobilization.
MedLine Citation:
PMID:  8536589     Owner:  NLM     Status:  MEDLINE    
Changes of motor cortex organization after lesions in the nervous system can be demonstrated by mapping the motor cortex with transcranial magnetic stimulation. We studied cortical plasticity in 22 patients who had a unilateral immobilization of the ankle joint without peripheral nerve lesion. The motor cortex area of the inactivated tibial anterior muscle diminished compared to the unaffected leg without changes in spinal excitability or motor threshold. The area reduction was correlated to the duration of immobilization. It could be quickly reversed by voluntary muscle contraction. This indicates a functional (and not morphological) origin of the phenomenon.
J Liepert; M Tegenthoff; J P Malin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Electroencephalography and clinical neurophysiology     Volume:  97     ISSN:  0013-4694     ISO Abbreviation:  Electroencephalogr Clin Neurophysiol     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-02-06     Completed Date:  1996-02-06     Revised Date:  2008-09-09    
Medline Journal Info:
Nlm Unique ID:  0375035     Medline TA:  Electroencephalogr Clin Neurophysiol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  382-6     Citation Subset:  IM; S    
Department of Neurology, Ruhr University, Bochum, Germany.
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MeSH Terms
Brain Mapping
Evoked Potentials / physiology
Immobilization / physiology*
Middle Aged
Motor Cortex / physiology*

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