| Changes of brain magnetic resonance imaging findings after congenital aortic arch anomaly repair using regional cerebral perfusion in neonates and young infants. | |
| | |
MedLine Citation:
|
PMID: 21095351 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The objective of this prospective study is to compare magnetic resonance imaging (MRI) findings before and after surgery for repairing congenital aortic arch anomalies using regional cerebral perfusion. METHODS: Neurologic examinations that included brain MRI, brain sonography, and electroencephalograms were performed before and after surgery for congenital aortic arch anomalies and the accompanying intracardiac anomalies using regional cerebral perfusion in 11 neonates and young infants. RESULTS: The median age at operation was 11 days (range, 5 to 46). The diagnoses included coarctation of the aorta with accompanying intracardiac anomalies (n = 10) and interruption of the aortic arch (n = 1). Aortic arch repair was performed using regional cerebral perfusion through the right innominate artery (regional perfusion time: 25.6 ± 6.0 minutes) without cardiac arrest. Two patients had new postoperative lesions on postoperative brain MRI, and these were acute focal subdural hemorrhage (n = 1) and acute focal infarction (n = 1). However, they were without clinical significance. Periventricular leukomalacia was not observed on brain MRI. There was no significant change between the preoperative and postoperative findings on brain sonography and electroencephalograms. All the patients showed normal neurologic growth for a mean follow-up duration of 175.3 days (range: 25 to 497 days). CONCLUSIONS: There were newly developed lesions on the postoperative brain MRI in 2 of 11 patients, even though these patients showed normal brain sonography and electroencephalogram findings and normal neurologic development. Our regional cerebral perfusion protocol for aortic arch repair showed tolerable neurologic outcomes, and it did not induce periventricular leukomalacia. |
| | |
Authors:
|
Jae Gun Kwak; Woong-Han Kim; Jin Tae Kim; In-One Kim; Jong-Hee Chae |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: The Annals of thoracic surgery Volume: 90 ISSN: 1552-6259 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 2010 Dec |
Date Detail:
|
Created Date: 2010-11-24 Completed Date: 2011-01-18 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 1996-2000 Citation Subset: AIM; IM |
Copyright Information:
|
Copyright © 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Bucheon, Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aorta, Thoracic
/
abnormalities*,
surgery Aortic Diseases / congenital, surgery* Brain / blood supply*, physiology Cerebrovascular Circulation / physiology* Echoencephalography Electroencephalography Follow-Up Studies Humans Infant Infant, Newborn Magnetic Resonance Imaging / methods* Postoperative Period Prognosis Prospective Studies Regional Blood Flow / physiology Vascular Malformations / surgery* Vascular Surgical Procedures / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: J. Maxwell Chamberlain Memorial Paper for congenital heart surgery. Deep hypothermic circulatory arr...
Next Document: Hypothermic circulatory arrest increases permeability of the blood brain barrier in watershed areas.