Document Detail

Changes of Intraocular Pressure during Experimental Vitrectomy.
MedLine Citation:
PMID:  22559787     Owner:  NLM     Status:  Publisher    
Purpose: To compare the infusion pressure shown by a vitrectomy device with the actual intraocular pressure (IOP) observed during pars plana vitrectomy. Furthermore, we evaluated the effects of variable parameters on the actual IOP during vitrectomy surgery. Materials and methods: Porcine eyes were obtained within 24 h of slaughter. Actual IOP was measured by a digital manometer during vitrectomy using the vented gas forced infusion (VGFI) system, as well as the gravity system. We analyzed the actual IOP according to the groups divided by remnant volume of infusion fluid: (500 ml; control group, 250, 125, and 50 ml). Finally, actual IOP was determined after changing variable parameters such as cutting rate, vacuum pressure, and the VGFI setting. Results: Settings for a VGFI system and pressure supplied by a gravity system significantly correlated with actual IOP (r = 0.99, p = 0.0001; r = 0.99, and p = 0.0001). Actual IOP declined with decreasing volume of infusion fluid. If the volume of infusion fluid was <125 ml, actual IOP decreased significantly compared with the control group and the difference in actual IOP reflected a significant difference in the VGFI setting of 30 mmHg. Cutting rate as well as VGFI setting and vacuum pressure affected actual IOP. Conclusions: Infusion pressure shown by the vitrectomy device was similar to actual IOP in porcine eyes. However, volume of infusion fluid and variable parameters could change the actual IOP during pars plana vitrectomy. Our results may help to optimize the ideal parameters such as infusion pressure, vacuum pressure, and cutting rate of vitrectomy systems used to treat vitreoretinal diseases.
Seung Hoon Kim; Kyung Seek Choi
Related Documents :
12699397 - Pulse pressure: an important tool in cardiovascular pharmacology and therapeutics.
16844717 - Blood pressure and haemoglobin a1c are associated with microhaemorrhage in cadasil: a t...
19189077 - Arterial blood pressure during early sepsis and outcome.
17414657 - Blood pressure-dependent and independent effects of agents that inhibit the renin-angio...
11428167 - Function-structure relationship of elastic arteries in evolution: from microfibrils to ...
10226247 - Trough: peak ratios for antihypertensive agents: methodological considerations.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-4
Journal Detail:
Title:  Current eye research     Volume:  -     ISSN:  1460-2202     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8104312     Medline TA:  Curr Eye Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Ophthalmology, College of Medicine, Soonchunhyang University , Seoul , Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Tetrahelix Conformations and Transformation Pathways in Pt1-Pd12 Clusters.
Next Document:  The predictive validity of the Drinking-Related Cognitions Scale in alcohol-dependent patients under...