| Change of seizure frequency in pregnant epileptic women. | |
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MedLine Citation:
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PMID: 6411866 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of pregnancy on seizure frequency was monitored prospectively in 136 pregnancies of 122 epileptic women. Pregnancy did not influence the seizure frequency in 68 pregnancies (50%). In 50 pregnancies (37%) the number of seizures increased during pregnancy or puerperium. The seizure frequency decreased in 18 pregnancies (13%). In 34 out of 50 pregnancies (68%) the increase was associated with non-compliance with the drug regimen or sleep deprivation. In seven out of 18 pregnancies (39%) improvement was related to correction of non-compliance or sleep deprivation during the pregestational nine months. Insufficiently low plasma concentrations of antiepileptic drugs were found in 47% of the women with uncontrolled epilepsy during pregnancy. The course of epilepsy during pregnancy is primarily influenced by non-compliance, sleep deprivation during pregnancy, and inadequate therapy before and during pregnancy. With good medical attention pregnancy itself seems to have only a minimal influence on the course of epilepsy. |
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Authors:
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D Schmidt; R Canger; G Avanzini; D Battino; C Cusi; G Beck-Mannagetta; S Koch; D Rating; D Janz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of neurology, neurosurgery, and psychiatry Volume: 46 ISSN: 0022-3050 ISO Abbreviation: J. Neurol. Neurosurg. Psychiatr. Publication Date: 1983 Aug |
Date Detail:
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Created Date: 1983-10-28 Completed Date: 1983-10-28 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985191R Medline TA: J Neurol Neurosurg Psychiatry Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 751-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anticonvulsants / administration & dosage* Epilepsies, Partial / diagnosis Epilepsy / diagnosis*, drug therapy Epilepsy, Temporal Lobe / diagnosis Female Humans Patient Compliance Pregnancy Pregnancy Complications / diagnosis*, drug therapy Prospective Studies Puerperal Disorders / diagnosis Sleep Deprivation |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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