Document Detail

Change of the initiation time of blood coagulation in pregnancy from 10-months to postpartum.
MedLine Citation:
PMID:  22475689     Owner:  NLM     Status:  Publisher    
We measured the time of initiation of blood coagulation (Ti) from pregnancy 10-months (36~40 weeks) till 1-month after delivery, paying particular attention to the very early postpartum period, using a damped oscillation rheometer that is approximately 160 times more sensitive than the Thromboelastogram® to evaluate the risk of thrombus formation. Blood samples were obtained from healthy volunteers at pregnancy 10-month, 1-hour, 3-hours, 4-days, 7-days, 3-weeks and 1-month after delivery. Ti values at pregnancy 10-month, 1-hour, 3-hours, 4-days, 7-days, 3-weeks, 1-month after delivery and in non-pregnant females were 20.4 ± 2.2, 11.7 ± 1.6, 13.2 ± 3.1, 17.2 ± 2.0, 20.2 ± 1.6, 21.4 ± 4.0, 24.6 ± 3.6, and (25.0 ± 3.4) minutes, respectively. Ti was significantly shorter at pregnancy 10-month, 1-hour, 3-ours, 4-days, 7-days and 3-weeks after delivery than in non-pregnant females. These data show that the blood of pregnant females is more hypercoagulable than non-pregnant females from pregnancy 10-month until 3-weeks post delivery, suggesting that they are at high risk of VTE after discharge from hospital.
Toshiaki Sagesaka; Hiroyuki Funabashi
Related Documents :
6260889 - Extracellular matrix synthesis in the chick embryo lateral plate prior to and during li...
16826069 - Viscoelastic and histologic properties in scarred rabbit vocal folds after mesenchymal ...
6658449 - Trace element changes in hair during pregnancy: preliminary study.
22506729 - Male gender promotes an increased inflammatory response to lipopolysaccharide (lps) in ...
2117839 - Immunofluorescence-microscopic localization of collagen type iv and vi, laminin and nid...
15645109 - Impairment of hair mechanical properties by sun exposure and bleaching treatments.
25218549 - Reproductive and obstetric outcome after laparoscopic excision of functional, non-commu...
19386409 - Fetal volume and crown-rump length from 7 to 10 weeks of gestational age in singletons ...
1381469 - Lower birth weight of offspring born after self-poisoning of parent.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-4
Journal Detail:
Title:  Clinical hemorheology and microcirculation     Volume:  -     ISSN:  1875-8622     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9709206     Medline TA:  Clin Hemorheol Microcirc     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Obstetrics and Gynecology, International University of Health and Welfare, Atami Hospital, Atami-shi, Shizuoka, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  EGFR protein overexpression correlates with chromosome 7 polysomy and poor prognostic parameters in ...
Next Document:  Consensus on the Clinical Impact of the New Scientific Evidence Available on Benign Prostatic Hyperp...