| Change in clinical status, health status, and health utility outcomes in HIV-infected patients. | |
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MedLine Citation:
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PMID: 7723445 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Psychometric health status scales and health utility scales were compared to measure the impact of changes in clinical status in patients infected with the human immunodeficiency virus (HIV). The data used included the first two waves of a longitudinal study of 160 HIV-infected patients, a population that was 34% women and 65% African American. The Medical Outcome Study-HIV Health Survey (MOS-HIV); sleep, cognitive function, and depression scales; the Sickness Impact Profile Home Management Scale; and questions on HIV-related clinical symptoms were administered. Standard gamble utilities and categorical rating scale preferences were assessed for current health state. The MOS-HIV scale scores of asymptomatic patients were significantly higher than those of symptomatic patients and patients with acquired immune deficiency syndrome. No differences were observed for utilities. Increases in clinical symptoms over 4 months were associated with changes in health perception, pain, physical role function, social function, mental health, depression, energy, cognitive function, and categorical rating scale preferences. The MOS-HIV and other health status measures discriminated between HIV disease stages and were associated with clinical status. Standard gamble utilities did not discriminate among the three groups and were not correlated with clinical status. |
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Authors:
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D A Revicki; A W Wu; M I Murray |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Medical care Volume: 33 ISSN: 0025-7079 ISO Abbreviation: Med Care Publication Date: 1995 Apr |
Date Detail:
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Created Date: 1995-05-25 Completed Date: 1995-05-25 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0230027 Medline TA: Med Care Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: AS173-82 Citation Subset: IM; X |
Affiliation:
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Medical Technology Assessment Program, Battelle Centers for Public Health Research and Evaluation, Arlington, VA 22201, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acquired Immunodeficiency Syndrome
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physiopathology*,
psychology Adult Female Health Status* Health Status Indicators Humans Longitudinal Studies Male Outcome Assessment (Health Care)* Psychometrics Quality of Life* Severity of Illness Index |
| Grant Support | |
ID/Acronym/Agency:
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HS06727/HS/AHRQ HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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