| Change in Hemostatic Intervention After Implementation of Thromboelastometry. | |
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MedLine Citation:
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PMID: 21924638 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To monitor the use of blood products and hemostatic intervention after implementation of thromboelastometry. DESIGN: Observational prospective study using a historic control. SETTING: Single-center university hospital. PARTICIPANTS: Patients undergoing cardiac surgery during 2008 (n = 811) were compared with similar patients in 2009 (n = 865). INTERVENTIONS: Thromboelastometry was implemented in December 2008. Changes in transfusion of blood products and changes in use of recombinant factor VIIa and fibrinogen were studied. MEASUREMENTS AND MAIN RESULTS: Use of blood products was not decreased significantly after implementation of thromboelastometry. However, in patients receiving blood products, the units of red blood cells were decreased significantly (p = 0.04). Regarding hemostatic reagents, the use of recombinant factor VIIa was decreased significantly (p = 0.04), and the use of fibrinogen increased significantly (p < 0.001). Most blood products (>70%) were given to a minority of patients (∼10%) in 2008 and 2009. In 2009, thromboelastometry was performed in 146 patients (17%), and the use of blood products (p < 0.0001), recombinant factor VIIa (p < 0.001), and fibrinogen (p < 0.001) was significantly higher compared with patients in whom thromboelastometry was not performed. CONCLUSIONS: After implementation of thromboelastometry, the use of recombinant factor VIIa was decreased significantly, whereas the use of blood products was not decreased significantly in patients undergoing cardiac surgery. |
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Authors:
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Anne-Mette Hvas; Tue Wincentz Boas; Malene Jensen; Christian Lindskov; Lars Folkersen; Hanne Berg Ravn |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-14 |
Journal Detail:
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Title: Journal of cardiothoracic and vascular anesthesia Volume: - ISSN: 1532-8422 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9110208 Medline TA: J Cardiothorac Vasc Anesth Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011. Published by Elsevier Inc. |
Affiliation:
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Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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