Document Detail


Chance of aneurysm in patients suspected of SAH who have a 'negative' CT scan but a 'positive' lumbar puncture.
MedLine Citation:
PMID:  21901483     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In patients with sudden severe headache and a negative computed tomography (CT) scan, a lumbar puncture (LP) is performed to rule in or out a subarachnoid haemorrhage (SAH), but this procedure is under debate. In a hospital-based series of 30 patients with sudden headache, a negative CT scan but a positive LP (defined as detection of bilirubin >0.05 at wavelength 458 nm), we studied the chance of harbouring an aneurysm and the clinical outcome. Aneurysms were found in none of both patients who presented within 3 days, in 8 of the 18 (44%) who presented within 4-7 days and in 5 of the 10 (50%) who presented within 8-14 days. Of the 13 patients with an aneurysm, 3 (23%) had poor outcome. In patients who present late after sudden headache, the yield in terms of aneurysms is high in those who have a positive lumbar puncture. In patients with an aneurysm as cause of the positive lumbar puncture, outcome is in the same range as in SAH patients admitted in good clinical condition.
Authors:
P Horstman; F H H Linn; H A M Voorbij; G J E Rinkel
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Publication Detail:
Type:  Journal Article     Date:  2011-09-08
Journal Detail:
Title:  Journal of neurology     Volume:  259     ISSN:  1432-1459     ISO Abbreviation:  J. Neurol.     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-04-05     Completed Date:  2012-08-03     Revised Date:  2013-06-27    
Medline Journal Info:
Nlm Unique ID:  0423161     Medline TA:  J Neurol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  649-52     Citation Subset:  IM    
Affiliation:
The Department of Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Bilirubin / cerebrospinal fluid
Female
Headache Disorders, Primary / etiology
Humans
Intracranial Aneurysm / cerebrospinal fluid,  complications,  radiography
Male
Middle Aged
Spinal Puncture
Subarachnoid Hemorrhage / cerebrospinal fluid*,  complications,  etiology,  radiography*
Time Factors
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
635-65-4/Bilirubin
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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