| Challenging the Sterrad 100NX sterilizer with different carrier materials and wrappings under experimental "clean" and "dirty" conditions. | |
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MedLine Citation:
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PMID: 20869138 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND: Sterrad sterilizers have been developed for the sterilization of thermolabile materials. The aim of the present study was to challenge the efficacy of this low-temperature hydrogen peroxide-based sterilization system with different carrier materials and wrappings under experimental "clean" and "dirty" conditions. METHODS: We tested the sporocidal effect of the Sterrad 100NX sterilizer (Advanced Sterilization Products, Irvine, CA) on the carrier materials titanium, polyethylene, and polyurethane with single versus 3 wrappings of inoculated carriers. To simulate insufficient cleaning or crystalline residues, carriers were charged with spore inocula containing organic and inorganic burdens. RESULTS: Our qualitative results show that irrespective of the number of wrappings in the "clean" condition, sterilization by the Sterrad 100NX was equally effective on all 3 carrier materials, reaching a log-10 reduction rate of ≥ 6 under standard half-cycle conditions. Any additional organic or inorganic challenge significantly impaired the sterilization outcome. CONCLUSION: Results of our current study emphasize the utmost importance of thorough and reliable cleaning of medical devices before being exposed to a subsequent hydrogen peroxide sterilization process. Any institution using this sterilization technology should have a well-established and validated cleaning process and enforce a rigorous quality assurance program for all steps of the presterilization processing of medical devices. |
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Authors:
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Magda Diab-Elschahawi; Alexander Blacky; Nicole Bachhofner; Walter Koller |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-09-24 |
Journal Detail:
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Title: American journal of infection control Volume: 38 ISSN: 1527-3296 ISO Abbreviation: Am J Infect Control Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8004854 Medline TA: Am J Infect Control Country: United States |
Other Details:
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Languages: eng Pagination: 806-10 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved. |
Affiliation:
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Clinical Institute of Hospital Hygiene, Vienna General Hospital, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, Austria. magda.diab-elschahawi@meduniwien.ac.at |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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