| Challenges and recommendations for placebo controls in randomized trials in physical and rehabilitation medicine: a report of the international placebo symposium working group. | |
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MedLine Citation:
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PMID: 20090428 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Compared with other specialties, the field of physical and rehabilitation medicine has not received the deserved recognition from clinicians and researchers in the scientific community. One of the reasons is the lack of sound evidence to support the traditional physical and rehabilitation medicine treatments. The best way to change this disadvantage is through a well conducted clinical research, such as standard placebo- or sham-controlled randomized clinical trials. Therefore, having placebo groups in clinical trials is essential to improve the level of evidence-based practice in physical and rehabilitation medicine that ultimately translates to better clinical care. To address the challenges for the use of placebo in physical and rehabilitation medicine and randomized clinical trials and to create useful recommendations, we convened a working group during the inaugural International Symposium in Placebo (February 2009, in Sao Paulo, Brazil) in which the following topics were discussed: (1) current status of randomized clinical trials in physical and rehabilitation medicine, (2) challenges for the use of placebo in physical and rehabilitation medicine, (3) bioethics, (4) use of placebo in acupuncture trials and for the treatment of low-back pain, (5) mechanisms of placebo, and (6) insights from other specialties. The current article represents the consensus report from the working group. |
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Authors:
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Felipe Fregni; Marta Imamura; Hsin Fen Chien; Henry L Lew; Paulo Boggio; Ted J Kaptchuk; Marcelo Riberto; Wu Tu Hsing; Linamara Rizzo Battistella; Andrea Furlan; |
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Publication Detail:
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Type: Journal Article; Practice Guideline; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of physical medicine & rehabilitation / Association of Academic Physiatrists Volume: 89 ISSN: 1537-7385 ISO Abbreviation: Am J Phys Med Rehabil Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-01-21 Completed Date: 2010-02-16 Revised Date: 2011-07-22 |
Medline Journal Info:
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Nlm Unique ID: 8803677 Medline TA: Am J Phys Med Rehabil Country: United States |
Other Details:
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Languages: eng Pagination: 160-72 Citation Subset: AIM; IM |
Affiliation:
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Harvard Medical School, Boston, Massachusetts, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Child Humans Patient Selection / ethics Physical Medicine / standards* Placebos / standards* Professional-Patient Relations / ethics Randomized Controlled Trials as Topic / standards* Rehabilitation / standards* |
| Grant Support | |
ID/Acronym/Agency:
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K24 AT004095/AT/NCCAM NIH HHS; K24 AT004095-01/AT/NCCAM NIH HHS; K24 AT004095-03/AT/NCCAM NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Placebos |
| Comments/Corrections | |
Comment In:
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Am J Phys Med Rehabil. 2010 Dec;89(12):1045-6; author reply 1046-7
[PMID:
21403596
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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