| Challenges of managing chronic pain in the elderly. | |
MedLine Citation:
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PMID: 12528073 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Effective management of chronic pain in the elderly has posed a formidable challenge to the medical community. Practicing physicians are confronted with the complexity of controlling chronic pain in a patient population that often presents with multiple health problems and side effects from long-term use of pain medications. This study presents an overview of commonly encountered barriers to effective management of pain in the elderly and suggests strategies to optimize treatment in this patient population. A high incidence of comorbidities in the elderly frequently necessitates the use of multiple therapies, the combination of which potentially increases the toxicity experienced by this population, which is already particularly susceptible to medication side effects. When determining optimal strategy for managing chronic pain in the elderly, particular attention needs to be paid to past medical history and use of over-the-counter medications. In addition, careful monitoring of age-related changes in physiologic functions is needed, as they may impact drug plasma concentrations and increase susceptibility to adverse events. When traditional pharmacologic agents (such as acetaminophen and nonselective nonsteroidal anti-inflammatory drugs) are deemed inappropriate in high-risk patients because of ineffectiveness or side effects, physicians must consider the use of alternative drugs, such as coxibs, which have comparable efficacy to traditional analgesics, with a superior side effects profile. |
Authors:
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Gary E Ruoff |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Seminars in arthritis and rheumatism Volume: 32 ISSN: 0049-0172 ISO Abbreviation: Semin. Arthritis Rheum. Publication Date: 2002 Dec |
Date Detail:
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Created Date: 2003-01-15 Completed Date: 2003-04-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 1306053 Medline TA: Semin Arthritis Rheum Country: United States |
Other Details:
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Languages: eng Pagination: 43-50 Citation Subset: IM |
Copyright Information:
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Copyright 2002, Elsevier Science (USA). All rights reserved. |
Affiliation:
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Department of Family Practice, Michigan State University College of Medicine, East Lansing, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged* Anti-Inflammatory Agents, Non-Steroidal / contraindications* Cyclooxygenase Inhibitors / contraindications* Health Services for the Aged* Humans Pain / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents, Non-Steroidal; 0/Cyclooxygenase Inhibitors |
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