Document Detail

Challenges in reducing the burden of otitis media disease: an ENT perspective on improving management and prospects for prevention.
MedLine Citation:
PMID:  20409595     Owner:  NLM     Status:  MEDLINE    
Acute otitis media (AOM) is a major public health concern. This frequent disease of childhood is a leading cause of physician visits, a major component of paediatric healthcare burden, and a key contributor to antibiotic resistance. An international expert group comprising mainly ear, nose, and throat physicians met in June 2008 to discuss the optimal management of AOM, particularly with regards to unmet needs in diagnosis and management. Current guidelines do not help identify which patients are most at risk for severe or complicated AOM. Diagnosis of AOM is also complicated by a lack of correlation between clinical signs and symptoms and responsible pathogens. Consequently, treatment of AOM is not always appropriate, and the long-term overuse of antibiotics in AOM reduces the effectiveness of treatment and places children at risk for drug-resistant infections. There is a need for educational and research initiatives to improve diagnostic accuracy and management of AOM. Because there is currently no ideal treatment, vaccination is an attractive additional approach for managing AOM and reducing its burden.
Gerhard Grevers;
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2010-04-20
Journal Detail:
Title:  International journal of pediatric otorhinolaryngology     Volume:  74     ISSN:  1872-8464     ISO Abbreviation:  Int. J. Pediatr. Otorhinolaryngol.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-14     Completed Date:  2010-09-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003603     Medline TA:  Int J Pediatr Otorhinolaryngol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  572-7     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.
ENT-Center, Prinzenweg 1, 82319 Starnberg, Germany.
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MeSH Terms
Acute Disease
Anti-Bacterial Agents / adverse effects,  therapeutic use*
Child Health Services / organization & administration
Child, Preschool
Cost of Illness*
Dose-Response Relationship, Drug
Drug Resistance, Multiple, Bacterial / drug effects
Haemophilus Infections / complications,  drug therapy
Haemophilus Vaccines / therapeutic use
International Cooperation
Middle Ear Ventilation / methods
Otitis Media* / complications,  microbiology,  prevention & control
Otolaryngology / methods*
Quality of Life / psychology
Streptococcal Infections / complications,  drug therapy
Streptococcal Vaccines / therapeutic use
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Haemophilus Vaccines; 0/Streptococcal Vaccines
Martine François / ; Gerhard Grevers / ; Alberto Leiberman / ; Eugene Leibovitz / ; Heidrun Muller / ; Thomas Nikolopoulos / ; Blake Papsin / ; Desiderio Passali / ; Maroeska M Rovers / ; Tania Sih / ; Ian Williamson /

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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