Document Detail

Challenges in recognition and diagnosis of yaws in children in Papua New Guinea.
MedLine Citation:
PMID:  21734134     Owner:  NLM     Status:  MEDLINE    
A global resurgence of yaws in developing countries highlights the need for reliable diagnostic criteria for this neglected infection. We conducted a clinical and serologic survey of 233 children less than 15 years of age who had clinically suspected yaws. A total of 138 (59%) cases were confirmed serologically, and 10 of 12 primary stage cases showed positive results for Treponema pallidum by a polymerase chain reaction assay that has not yet been validated for identification of yaws. A high proportion of cases (46%) were in the secondary stage; 92% of them had osteoarticular involvement, and only 24% had a Venereal Disease Research Laboratory titer greater than 1:32.
Oriol Mitjà; Russell Hays; Francis Lelngei; Nedley Laban; Anthony Ipai; Slim Pakarui; Quique Bassat
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Validation Studies    
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  85     ISSN:  1476-1645     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-07-07     Completed Date:  2011-09-15     Revised Date:  2013-06-28    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  113-6     Citation Subset:  AIM; IM    
Department of Medicine, and Department of Microbiology, Lihir Medical Centre, International SOS, Lihir Island, Papua New Guinea.
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MeSH Terms
Child, Preschool
Papua New Guinea / epidemiology
Polymerase Chain Reaction
Sensitivity and Specificity
Yaws / diagnosis*,  epidemiology

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