Document Detail


Challenges in the epidemiological and clinical aspects of Burkitt's lymphoma in Kenya: linking evidence and experience.
MedLine Citation:
PMID:  15622609     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: In a series of 1005 cases of Burkitt's lymphoma studied for epidemiological and clinical characteristics, some features remain less obvious contrary to what is commonly held about this disease. OBJECTIVES: To use the case series to document the challenges in the epidemiological and clinical characteristics of Burkitt's lymphoma (BL) in Kenya. DESIGN: Cross sectional study involving clinical review of case series. SETTING: Kenyatta National Hospital and the seven provincial hospitals in Kenya during the period between 1986 and 1996. DATA SOURCES: Systematic review of the epidemiological and clinical features of the 1005 cases enrolled in the case study and review of reference lists of retrieved articles to identify original research dealing with the epidemiological and clinical features of Burkitt's lymphoma. DATA EXTRACTION: The investigators and research assistants screened both the case series and published information and data to yield relevant information. CONCLUSION: The majority of Burkitt's lymphoma cases between the age group three and nine years of age coincide with the established epidemiological and clinical characteristics. The adult BL cases and some childhood cases however do not conform entirely to the established characteristics. Therefore, making the diagnosis of Burkitt's lymphoma require that; geographical, demographical, clinical features as well as any underlying infections for instance, Human Immunodeficiency Virus be taken into consideration.
Authors:
O W Mwanda; R Rochford; J Rainey; M L Wilson
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  East African medical journal     Volume:  -     ISSN:  0012-835X     ISO Abbreviation:  East Afr Med J     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-12-24     Completed Date:  2005-02-10     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372766     Medline TA:  East Afr Med J     Country:  Kenya    
Other Details:
Languages:  eng     Pagination:  S111-6     Citation Subset:  IM    
Affiliation:
Department of Haematology and Blood Transfusion, College of Health Sciences, University of Nairobi, Kenya.
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Burkitt Lymphoma / diagnosis*,  epidemiology*
Cross-Sectional Studies
Ethnic Groups
HIV Infections / epidemiology
Humans
Kenya / epidemiology
Sex Factors
Grant Support
ID/Acronym/Agency:
AI-36219/AI/NIAID NIH HHS

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