| Challenges in the classification of atrial fibrillation. | |
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MedLine Citation:
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PMID: 20567238 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The incidence and prevalence of atrial fibrillation (AF) are increasing worldwide. AF is of public health importance because it accounts for substantial morbidity, mortality, and health-care costs. AF may be transient initially, but many patients have progressive disease marked by increasing frequency and duration of episodes. Various classification schemes for AF have been proposed, although current guidelines are based on temporal rhythm-based patterns. We discuss existing schemes for the classification of AF, focusing on the advantages and limitations of the pattern-based scheme, in the context of new knowledge about AF pathophysiology, AF patterns, and clinical outcomes. Furthermore, we address gaps in knowledge that present opportunities to re-examine the current pattern-based classification of AF. A future classification scheme should ideally combine elements such as the risk of stroke, an assessment of symptoms, and the degree of impairment of the atrial substrate. |
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Authors:
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Steven A Lubitz; Emelia J Benjamin; Jeremy N Ruskin; Valentin Fuster; Patrick T Ellinor |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Review Date: 2010-06-22 |
Journal Detail:
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Title: Nature reviews. Cardiology Volume: 7 ISSN: 1759-5010 ISO Abbreviation: Nat Rev Cardiol Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-26 Completed Date: 2010-11-08 Revised Date: 2011-07-28 |
Medline Journal Info:
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Nlm Unique ID: 101500075 Medline TA: Nat Rev Cardiol Country: England |
Other Details:
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Languages: eng Pagination: 451-60 Citation Subset: IM |
Affiliation:
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Cardiovascular Research Center, Massachusetts General Hospital, 149 13th Street, 4th Floor, Charlestown, MA 02129, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Atrial Fibrillation
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classification*,
diagnosis,
physiopathology,
therapy Atrial Function* Disease Progression Electrocardiography Heart Conduction System / physiopathology* Heart Rate* Humans Predictive Value of Tests Prognosis Severity of Illness Index Terminology as Topic* |
| Grant Support | |
ID/Acronym/Agency:
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AG028321/AG/NIA NIH HHS; DA027021/DA/NIDA NIH HHS; HL092577/HL/NHLBI NIH HHS; R21 DA027021-02/DA/NIDA NIH HHS; RC1-HL01056/HL/NHLBI NIH HHS; T32 HL007575-27/HL/NHLBI NIH HHS; T32HL007575/HL/NHLBI NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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