Document Detail


Challenges facing JAK inhibitor therapy for myeloproliferative neoplasms.
MedLine Citation:
PMID:  22375977     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Authors:
Ayalew Tefferi
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Publication Detail:
Type:  Comment; Editorial    
Journal Detail:
Title:  The New England journal of medicine     Volume:  366     ISSN:  1533-4406     ISO Abbreviation:  N. Engl. J. Med.     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-03-01     Completed Date:  2012-03-08     Revised Date:  2012-05-24    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  844-6     Citation Subset:  AIM; IM    
Export Citation:
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Janus Kinase 1 / antagonists & inhibitors*
Janus Kinase 2 / antagonists & inhibitors*
Male
Primary Myelofibrosis / drug therapy*
Protein Kinase Inhibitors / therapeutic use*
Pyrazoles / therapeutic use*
Splenomegaly / drug therapy*
Chemical
Reg. No./Substance:
0/INCB018424; 0/Protein Kinase Inhibitors; 0/Pyrazoles; EC 2.7.10.1/Janus Kinase 1; EC 2.7.10.1/Janus Kinase 2
Comments/Corrections
Comment On:
N Engl J Med. 2012 Mar 1;366(9):787-98   [PMID:  22375970 ]
N Engl J Med. 2012 Mar 1;366(9):799-807   [PMID:  22375971 ]
Comment In:
N Engl J Med. 2012 May 24;366(21):2032; author reply 2032-5   [PMID:  22621635 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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