Document Detail

Challenges, concerns and common problems: physiological consequences of spinal cord injury and microgravity.
MedLine Citation:
PMID:  20498665     Owner:  NLM     Status:  In-Process    
INTRODUCTION: Similarities between the clinical presentation of individuals living with spinal cord injury (SCI) and astronauts are remarkable, and may be of great interest to clinicians and scientists alike.
OBJECTIVES: The primary purpose of this review is to outline the manner in which cardiovascular, musculoskeletal, renal, immune and sensory motor systems are affected by microgravity and SCI.
METHODS: A comprehensive review of the literature was conducted (using PubMed) to evaluate the hallmark symptoms seen after spaceflight and SCI. This literature was then examined critically to determine symptoms common to both populations.
RESULTS: Both SCI and prolonged microgravity exposure are associated with marked deteriorations in various physiological functions. Atrophy in muscle and bone, cardiovascular disturbances, and alterations in renal, immune and sensory motor systems are conditions commonly observed not only in individuals with SCI, but also in those who experience prolonged gravity unloading.
CONCLUSION: The preponderance of data indicates that similar physiological changes occur in both SCI and prolonged space flight. These findings have important implications for future research in SCI and prolonged space flight.
J M Scott; D E R Warburton; D Williams; S Whelan; A Krassioukov
Related Documents :
15936395 - Extremely rare glioblastoma multiforme of the conus medullaris with holocord and brain ...
21051925 - Regrowth of septal spur in split cord malformation.
8861315 - Spinal meningeal melanocytoma: a case report and review of the literature.
7732475 - Metastatic paraganglioma causing spinal cord compression.
7805415 - Tularemia.
1483405 - Laryngeal chondrosarcoma: diagnosis and management.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-05-25
Journal Detail:
Title:  Spinal cord : the official journal of the International Medical Society of Paraplegia     Volume:  49     ISSN:  1476-5624     ISO Abbreviation:  Spinal Cord     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9609749     Medline TA:  Spinal Cord     Country:  England    
Other Details:
Languages:  eng     Pagination:  4-16     Citation Subset:  IM    
Cardiovascular Physiology and Rehabilitation Laboratory, Department of Education, University of British Columbia, Vancouver, British Columbia, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Cardiac pacing in patients with a cervical spinal cord injury.
Next Document:  The Oncofertility Consortium--addressing fertility in young people with cancer.