Document Detail

Challenges associated with hypertensive disease during pregnancy in low-income countries.
MedLine Citation:
PMID:  20362990     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the challenges associated with the diagnosis, management, and prevention of hypertensive disease during pregnancy in low-income countries, following the success of the Magpie Trial. METHODS: Descriptive review of the literature from 1990 to 2009 on the diagnosis, management, and prevention of hypertensive disease in pregnancy. RESULTS: In the absence of credible measures to predict and prevent hypertension in pregnancy, diagnosis and treatment remain the only viable options, although they are still associated with important challenges in low-income countries. Despite the presence of high-quality evidence that magnesium sulfate is safe and effective at preventing and treating eclampsia, its use is extremely limited in many low-income countries. CONCLUSION: There is a need for cheap and reliable tools with which to address the diagnostic, preventive, and management challenges associated with hypertensive disease during pregnancy in low-income countries. It is recommended that such countries incorporate magnesium sulfate protocols into their national health and/or practice policies.
Kwabena A Danso; Henry S Opare-Addo
Publication Detail:
Type:  Journal Article; Review     Date:  2010-04-02
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  110     ISSN:  1879-3479     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-08-04     Completed Date:  2010-11-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  78-81     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
Department of Obstetrics and Gynaecology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
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MeSH Terms
Anticonvulsants / adverse effects,  therapeutic use
Antihypertensive Agents / adverse effects,  therapeutic use*
Developing Countries
Eclampsia / drug therapy,  prevention & control
Hypertension, Pregnancy-Induced / diagnosis,  drug therapy*,  prevention & control
Magnesium Sulfate / adverse effects,  therapeutic use*
Reg. No./Substance:
0/Anticonvulsants; 0/Antihypertensive Agents; 7487-88-9/Magnesium Sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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