| Chalcones and their potential role in inflammation. | |
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MedLine Citation:
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PMID: 18855737 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of protective pathways offering a promising stratagem for therapeutic applications. In this research we will review the anti-inflammatory effect of chalcone derivatives and new approaches. |
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Authors:
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C Kontogiorgis; M Mantzanidou; D Hadjipavlou-Litina |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Mini reviews in medicinal chemistry Volume: 8 ISSN: 1389-5575 ISO Abbreviation: Mini Rev Med Chem Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-10-15 Completed Date: 2009-01-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101094212 Medline TA: Mini Rev Med Chem Country: Netherlands |
Other Details:
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Languages: eng Pagination: 1224-42 Citation Subset: IM |
Affiliation:
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Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotle University of Thessaloniki, Thessaloniki, Greece. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anti-Inflammatory Agents / pharmacology Antioxidants / metabolism Chalcones / pharmacology* Chemistry, Pharmaceutical / methods Drug Design Free Radical Scavengers Humans Inflammation* Leukotriene B4 / chemistry Models, Biological Models, Chemical Neutrophils / metabolism Oxygen / chemistry Phenol / chemistry |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 0/Antioxidants; 0/Chalcones; 0/Free Radical Scavengers; 108-95-2/Phenol; 71160-24-2/Leukotriene B4; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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