Document Detail

Chains, sheets, and droplets: assemblies of hydrophobic gold nanocrystals with saturated phosphatidylcholine lipid and squalene.
MedLine Citation:
PMID:  23033891     Owner:  NLM     Status:  MEDLINE    
Assemblies of saturated 1,2-diacylphosphatidylcholine lipid and hydrophobic dodecanethiol-capped 1.8 nm diameter gold nanocrystals were studied as a function of lipid chain length and the addition of the naturally occurring oil, squalene. The gold nanocrystals formed various lipid-stabilized agglomerates, sometimes fusing with lipid vesicle bilayers. The nanocrystal assembly structure depended on the hydrocarbon chain length of the lipid fatty acids. The lipid with the shortest fatty acid length studied, dilauroylphosphatidylcholine, created extended chains of gold nanocrystals. The lipid with slightly longer fatty acid chains created planar sheets of nanocrystals. Further increases of the fatty acid chain length led to spherical agglomerates. The inclusion of squalene led to lipid- and nanocrystal-coated oil droplets.
Michael R Rasch; Christian A Bosoy; Yixuan Yu; Brian A Korgel
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2012-10-17
Journal Detail:
Title:  Langmuir : the ACS journal of surfaces and colloids     Volume:  28     ISSN:  1520-5827     ISO Abbreviation:  Langmuir     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-30     Completed Date:  2013-03-26     Revised Date:  2013-11-04    
Medline Journal Info:
Nlm Unique ID:  9882736     Medline TA:  Langmuir     Country:  United States    
Other Details:
Languages:  eng     Pagination:  15160-7     Citation Subset:  IM    
Department of Chemical Engineering, Texas Materials Institute, Center for Nano- and Molecular Science and Technology, The University of Texas at Austin, Austin, Texas 78712-1062, United States.
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MeSH Terms
Gold / chemistry*
Hydrophobic and Hydrophilic Interactions*
Lipid Bilayers / chemistry
Metal Nanoparticles / chemistry*
Phosphatidylcholines / chemistry*
Squalene / chemistry*
Grant Support
R01 CA132032/CA/NCI NIH HHS; R01 CA132032/CA/NCI NIH HHS
Reg. No./Substance:
0/Lipid Bilayers; 0/Phosphatidylcholines; 111-02-4/Squalene; 7440-57-5/Gold

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