Document Detail


Chagas disease as a cause of symptomatic chronic myocardopathy in Mexican children.
MedLine Citation:
PMID:  19859016     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the first case series of children in Mexico living with symptomatic Chagas disease causing chronic myocardopathy. The findings suggest that children with Chagas disease may develop symptomatic chronic myocardopathy earlier than previously recognized. Our findings emphasize the importance of longitudinal cardiologic follow-up of all children identified with acute Chagas disease.In a cohort of 826 children from the state of Queretaro in Mexico, 11 were identified with positive serology (ELISA and IFI) for Chagas and were tested for electrocardiogram alterations and symptoms and signs. Four children had ECG alterations with 3 of these reporting signs and symptoms associated with the chronic phase of Chagas disease (27%; 95% CI: 6%-61%). The most common chronic symptom was chest pain, with one child also reporting dyspnea and tachycardia.
Authors:
Paz Maria Salazar-Schettino; Rafael Perera; Adela Luisa Ruiz-Hernandez; Martha Irene Bucio Torres; Carlos Zamora-Gonzalez; Margarita Cabrera-Bravo; Anthony Harnden
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  28     ISSN:  1532-0987     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-27     Completed Date:  2010-02-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1011-3     Citation Subset:  IM    
Affiliation:
Laboratorio de Biolog?a de Par?sitos, Departmento de Microbiolog?a y Parasitolog?a, Facultad de Medicina, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Mexico, Distrito Federal, CP, Mexico. pazmar@servidor.unam.mx
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Antibodies, Protozoan / blood
Cardiomyopathies / epidemiology*,  etiology*,  pathology
Chagas Disease / complications*,  epidemiology*,  pathology
Chest Pain / etiology
Child
Child, Preschool
Cohort Studies
Dyspnea / etiology
Electrocardiography
Humans
Male
Mexico / epidemiology
Tachycardia / etiology
Chemical
Reg. No./Substance:
0/Antibodies, Protozoan

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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