Document Detail


Chagas disease: increased parasitemia during pregnancy detected by hemoculture.
MedLine Citation:
PMID:  21460012     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
One hundred fifty-two Trypanosoma cruzi seropositive women were submitted to a single hemoculture; 101 were pregnant, and 51 were not pregnant. Seven tubes from each individual were harvested with liver infusion tryptose (LIT) medium and observed monthly until the fifth month. Hemocultures were positive in 50% (76 of 152) of the women. Results showed that the positivity was 29.4% (15 of 51) among non-pregnant women and 60.4% (61 of 101) in pregnant women (P < 0.05). In relation to gestational age, there were significant differences in positivity, with a higher proportion of women with positive hemocultures (20 of 25) before 21 weeks and lower after 30 weeks (10 of 21; P = 0.02). We conclude that pregnancy enhances the parasitemia in Chagas disease, with a higher effect early in pregnancy.
Authors:
Liliane da Rocha Siriano; Alejandro Ostermayer Luquetti; Juliana Boaventura Avelar; Neusa Leal Marra; Ana Maria de Castro
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  84     ISSN:  1476-1645     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-04-04     Completed Date:  2011-06-07     Revised Date:  2012-04-05    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  569-74     Citation Subset:  AIM; IM    
Affiliation:
Laboratório de Pesquisa da doença de Chagas, Hospital das Clínicas and Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Blood / parasitology
Chagas Disease / blood*,  parasitology*
Female
Humans
Middle Aged
Pregnancy
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Central nervous system toxicity associated with liposomal amphotericin B therapy for cutaneous leish...
Next Document:  Humoral immune response against P2? from Trypanosoma cruzi in persons with chronic Chagas disease: i...