| Cesium toxicity: a case of self-treatment by alternate therapy gone awry. | |
| | |
MedLine Citation:
|
PMID: 12548155 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Cesium salts have been used in animal models to induce cardiac arrhythmias for several decades, but the sequelae of human cesium toxicity have seldom been described. The authors describe a case of cesium toxicity manifested by syncope, polymorphic ventricular tachycardia, hypokalemia, and a QT interval prolonged to 650 milliseconds that resolved over 4 days following withdrawal of cesium. The patient had a 2-year history of colon cancer and had self-treated with cesium chloride, 3 g/d, for several weeks, using cesium as a form of alternate therapy for cancer. The authors describe the pathophysiologic correlates and risks of cesium consumption and conclude that cesium toxicity should be considered among the differential diagnoses of prolonged QT interval. |
| | |
Authors:
|
Andrew W Lyon; William J Mayhew |
Related Documents
:
|
1306105 - Levels of colorectal ornithine decarboxylase activity in patients with colon cancer, a ... 2582455 - Reproductive and menstrual factors and risk of colorectal cancer. 3134175 - Effect of various biological factors on spontaneous marmoset and tamarin colitis. a ret... 3836135 - A non-absorbable rifamycin for treatment of hepatic encephalopathy. 23098465 - Health-related quality of life among breast cancer patients and its influencing factor ... 11221895 - Protoporphyrin ix occurs naturally in colorectal cancers and their metastases. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Therapeutic drug monitoring Volume: 25 ISSN: 0163-4356 ISO Abbreviation: Ther Drug Monit Publication Date: 2003 Feb |
Date Detail:
|
Created Date: 2003-01-27 Completed Date: 2003-07-09 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7909660 Medline TA: Ther Drug Monit Country: United States |
Other Details:
|
Languages: eng Pagination: 114-6 Citation Subset: IM |
Affiliation:
|
Department of Pathology and Laboratory Medicine, University of Calgary, Alberta, Canada. alyon@ucalgary.ca |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cesium
/
toxicity* Chlorides / toxicity* Complementary Therapies / adverse effects Female Humans Hypokalemia / chemically induced Middle Aged Self Medication / adverse effects* Tachycardia, Ventricular / chemically induced |
| Chemical | |
Reg. No./Substance:
|
0/Chlorides; 7440-46-2/Cesium; 7647-17-8/cesium chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Frequency distribution of C3435T mutation in exon 26 of the MDR1 gene in a Spanish population.
Next Document: High-performance liquid chromatographic analysis of the anticancer drug irinotecan (CPT-11) and its ...