Document Detail

Cervical ventral epidural pressure response to graded spinal canal compromise and spinal motion.
MedLine Citation:
PMID:  15247573     Owner:  NLM     Status:  MEDLINE    
STUDY DESIGN: A laboratory investigation using a feline model of graded ventral spinal canal compromise was performed. OBJECTIVE: To quantify the effects of graded ventral spinal canal compromise, both in the static condition and in combination with passive spinal motion, on cervical ventral epidural pressure (CVEP). The CVEP effects of laminectomy are also investigated. SUMMARY OF BACKGROUND DATA: Spinal canal compromise, both in the static condition and in combination with passive spinal motion, has been implicated as a cause of spinal cord dysfunction. METHODS: Seventeen cats underwent anterior corpectomy of C3 and placement of a flexible ventral graded compression device incorporating a pressure transducer. Ten animals also underwent laminectomy of C3. The implant was advanced stepwise into the spinal canal. CVEP was measured, at each degree of canal compromise, in the flexed, extended, and neutral positions, as well as during neck movement. RESULTS: CVEP rose as a function of spinal canal compromise. In animals without laminectomy, mean CVEP was higher in the extended position and lower in the flexed position than in the neutral position. Mean CVEP during continuous passive neck movement was found to be higher than mean CVEP in the neutral position. Laminectomy was found to lower CVEP during all conditions examined, although substantial rises in CVEP were still observed in the presence of a residual ventral mass. All reported differences were statistically significant (P < 0.05). CONCLUSIONS: CVEP is elevated by both spinal canal compromise and spinal motion.
Christopher E Wolfla; Brian E Snell; Johnnie H Honeycutt
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Spine     Volume:  29     ISSN:  1528-1159     ISO Abbreviation:  Spine     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-07-12     Completed Date:  2004-10-20     Revised Date:  2009-07-09    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1524-9     Citation Subset:  IM    
Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
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MeSH Terms
Cervical Vertebrae / surgery
Epidural Space*
Movement / physiology
Neck Muscles / physiology
Range of Motion, Articular
Spinal Canal
Spinal Cord Compression / physiopathology*
Transducers, Pressure

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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