Document Detail

Cervical spine disorders in patients with rheumatoid arthritis and amyloidosis.
MedLine Citation:
PMID:  12111629     Owner:  NLM     Status:  MEDLINE    
The aim of this radiographic study was to ascertain the extent of inflammatory cervical spine disorders in patients with rheumatoid arthritis (RA) complicated by secondary amyloidosis (SA). The study involved 147 patients with RA and SA, whose cervical spine radiographs were available. They were treated at the Rheumatism Foundation Hospital, Heinola, during the period 1989-2000 and had had RA for a mean of 24 years. The inflammatory abnormalities of the cervical spine were studied from radiographs taken at or after the diagnosis of SA during flexion and extension. One-hundred and eleven (76%) patients had subluxations, impaction or apophyseal joint ankylosis. Atlantoaxial impaction (AAI) was seen in 76 (52%) patients and anterior atlantoaxial subluxation (AAS) in 59 (40%). Apophyseal joint ankylosis was the third most frequent finding, seen in 34 (23%) cases. A combination of AAI and apophyseal joint ankylosis was noted in 26 (18%) patients. Eight (5%) patients had undergone surgery on the cervical spine. In conclusion, inflammatory and destructive changes are frequent in the cervical spine of patients with RA and SA. Characteristic changes are AAI and AAS. RA patients with SA have more severe disease than those in epidemiological studies when cervical spine disorders are concerned.
Kari Laiho; K Kaarela; M Kauppi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical rheumatology     Volume:  21     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-07-11     Completed Date:  2002-09-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  227-30     Citation Subset:  IM    
Rheumatism Foundation Hospital, FIN-18120 Heinola, Finland.
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MeSH Terms
Amyloidosis / etiology*
Ankylosis / etiology,  radiography
Arthritis, Rheumatoid / complications*,  radiography
Atlanto-Axial Joint / radiography
Cervical Vertebrae* / radiography
Dislocations / etiology,  radiography
Joint Deformities, Acquired / etiology,  radiography
Middle Aged
Spinal Diseases / etiology*,  radiography

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