Document Detail


Cervical radiculopathy secondary to Hodgkin's lymphoma.
MedLine Citation:
PMID:  17445629     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Spinal cord/root compression is a rare complication of HL and usually seen in the setting of progressive, advanced disease. It is extremely rare to occur as an initial presentation of HL. We report a case of HL presented with bilateral cervical radiculopathy. METHODS: A case report of a 42-year-old woman who presented with C8 cervical radiculopathy and paraspinal mass with extradural extension in C7-T1. Biopsy revealed HL. This case report represents a case of HL presenting with epidural disease, with nerve root compression as the only apparent site of clinical involvement. A review of the literature of patients with HL presenting with spinal cord/root compression is presented. RESULT: Our patient received chemotherapy and external beam radiation therapy. She achieved good recovery of her symptoms and complete response by radiologic criteria. Based on a review of the literature, Hodgkin's disease involving the spinal epidural space is very responsive to chemoradiotherapy with good prognosis for both functional recovery and complete response. CONCLUSION: Chemoradiotherapy is a successful treatment for Hodgkin's disease presenting with spinal root compression. Surgery should be reserved for urgent decompression, if needed; palliation; and maintenance of function and stability.
Authors:
Haitham Al-Khayat; Hisham Al-Khayat; Osama Al-Baker; Ala' Groof; Adnan Sadeq; Hussein Hayati; Zaki A Zarka
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Surgical neurology     Volume:  67     ISSN:  0090-3019     ISO Abbreviation:  Surg Neurol     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-20     Completed Date:  2007-07-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0367070     Medline TA:  Surg Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  540-3     Citation Subset:  IM    
Affiliation:
Department of Surgery, Saad Specialist Hospital, Al-Khobar 31952, Saudi Arabia. halkhayat@yahoo.com <halkhayat@yahoo.com>
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MeSH Terms
Descriptor/Qualifier:
Adult
Cervical Vertebrae / pathology
Drug Therapy
Epidural Space / pathology,  physiopathology
Female
Hodgkin Disease / complications*,  pathology*,  physiopathology
Humans
Magnetic Resonance Imaging
Neck Pain / etiology,  pathology,  physiopathology
Paresthesia / etiology,  pathology,  physiopathology
Radiculopathy / etiology*,  pathology*,  physiopathology
Radiotherapy
Spinal Canal / pathology,  physiopathology
Spinal Nerve Roots / pathology*,  physiopathology
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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