Document Detail

Cervical metastases in advanced ovarian malignancies.
MedLine Citation:
PMID:  8344319     Owner:  NLM     Status:  MEDLINE    
Cervical metastases from ovarian malignancies are a rare event. In order to better define the incidence and pathogenesis of this phenomenon we retrospectively reviewed the charts and pathologic material from 171 Stage III ovarian malignancies. Nine patients (5.3%) were identified with cervical metastases and three patterns of spread to the cervix were recognized: 1) lymphatic permeation only; 2) para-cervical soft tissue extension and 3) direct stromal myometrial invasion. All of the patients with cervical metastases had high grade (Broder's grade III or IV) tumors and extensive abdominal disease at presentation. Although four patients had a positive or suspicious pap smear, none of these had cervical involvement. We conclude that ovarian metastases to the cervix are a rare event, occurring late in the course of the disease and arise from a variety of modes of spread.
H M Tarraza; H G Muntz; M De Cain; M A Jones
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of gynaecological oncology     Volume:  14     ISSN:  0392-2936     ISO Abbreviation:  Eur. J. Gynaecol. Oncol.     Publication Date:  1993  
Date Detail:
Created Date:  1993-09-09     Completed Date:  1993-09-09     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8100357     Medline TA:  Eur J Gynaecol Oncol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  274-8     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Maine Medical Center, Portland.
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MeSH Terms
Adenocarcinoma / pathology,  secondary
Lymphatic Metastasis
Neoplasm Invasiveness
Ovarian Neoplasms / pathology*
Retrospective Studies
Uterine Cervical Neoplasms / pathology,  secondary*

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