| Cervical lymphadenopathy associated with Hashimoto's thyroiditis: an analysis of 22 cases by fine needle aspiration cytology. | |
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MedLine Citation:
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PMID: 19798875 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To analyze the possible association between Hashimoto's thyroiditis (HT) and cervical lymphadenopathy in cases diagnosed by fine needle aspiration cytology. STUDY DESIGN: Among the patients referred to our laboratory for ultrasound-guided fine needle aspiration cytology of thyroid nodules (USG-FNAC), cases of HT associated with cervical lymphadenopathy were evaluated. RESULTS: Between February 2001 and May 2007, HT was diagnosed in 94 (11%) of a total of 856 thyroid USG-FNAC cases. Among these cases, 22 (23%) were associated with single/ multiple cervical lymphadenopathy. In all cases, FNAC of the lymph nodes was consistent with reactive lymphoid hyperplasia. Anti-TPO and anti-Tg antibody results were obtained in 14 of 22 cases with HT. Among these cases, 12 showed positive values. CONCLUSION: Clinicians and cytopathologists who encounter thyroid nodules with cervical lymphadenopathy should also include the possibility of HT in the differential diagnosis. A literature search disclosed no report regarding the possible association between HT and cervical lymphadenopathy. Considering the limitations due to lack of immunocytochemical analysis of the thyroid and lymph node aspirates, our study should be taken as a preliminary one. |
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Authors:
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Nadir Paksoy; Kadri Yazal |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta cytologica Volume: 53 ISSN: 0001-5547 ISO Abbreviation: Acta Cytol. Publication Date: 2009 Sep-Oct |
Date Detail:
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Created Date: 2009-10-05 Completed Date: 2009-10-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370307 Medline TA: Acta Cytol Country: United States |
Other Details:
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Languages: eng Pagination: 491-6 Citation Subset: IM |
Affiliation:
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Paksoy's Cytopathology Laboratory, Izmit, Kocaeli, Turkey. citographica@superonline.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Autoantibodies / analysis Autoantigens / immunology Biopsy, Fine-Needle* / methods Case-Control Studies Female Hashimoto Disease / immunology, pathology* Humans Iodide Peroxidase / immunology Iron-Binding Proteins / immunology Lymphatic Diseases / pathology* Male Middle Aged Pilot Projects Predictive Value of Tests Thyroid Nodule / immunology, pathology* Ultrasonography, Interventional Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; 0/Autoantigens; 0/Iron-Binding Proteins; 0/anti-thyroglobulin; EC 1.11.1.7/TPO protein, human; EC 1.11.1.8/Iodide Peroxidase |
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