| Cervical length as a predictor of pre-term birth in twin gestations. | |
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MedLine Citation:
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PMID: 11463141 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to determine the predictive value of cervical length as a risk factor for spontaneous pre-term birth in twin gestations. A retrospective chart review was carried out on patients with twin pregnancies referred to our multiples' clinic. Cervical length was measured by transvaginal ultrasonography. Patients with an indicated pre-term delivery or intervention were excluded from the analysis. Outcomes included preterm delivery < 28 and < 35 weeks gestation. After extracting the data, 2 x 4 tables were constructed. Likelihood ratios were then generated for cervical lengths < or = 2.0 cm, < or = 2.5 cm, < or = 3.0 cm, and > 3.0 cm. Because of the limited number of measurements taken < 25 weeks gestation, we elected to collapse the tables, thereby achieving more meaningful results. For measurements taken before 30 weeks gestation, a shorter cervix did predict delivery < 28 weeks gestation (likelihood ratios for cervical lengths < or = 2.0 cm, < or = 2.5 cm, < or = 3.0 cm, and > 3.0 cm were 4.43, 1.94, 0.97, and 1.02, respectively). The probability of preterm delivery < 35 weeks gestation increased with decreasing cervical length (likelihood ratios for cervical length < or = 2.0 cm, < or = 2.5 cm, < or = 3.0 cm, and > 3.0 cm were 2.58, 1.66, 1.38, and 0.81, respectively). A shorter cervix measured before 30 weeks gestation was a stronger predictor of preterm delivery < 28 weeks compared to < 35 weeks gestation. Cervical length was not predictive of preterm delivery if measured after 30 weeks. Cervical length is predictive of preterm delivery < 28 weeks and < 35 weeks gestation when measured before 30 weeks gestation. No trend was seen when measured after 30 weeks gestation. A prospective study is currently underway to confirm these results. |
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Authors:
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J L Shapiro; R Kung; J F Barrett |
Publication Detail:
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Type: Journal Article; Validation Studies |
Journal Detail:
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Title: Twin research : the official journal of the International Society for Twin Studies Volume: 3 ISSN: 1369-0523 ISO Abbreviation: Twin Res Publication Date: 2000 Dec |
Date Detail:
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Created Date: 2001-07-20 Completed Date: 2001-08-09 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9815819 Medline TA: Twin Res Country: England |
Other Details:
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Languages: eng Pagination: 213-6 Citation Subset: IM |
Affiliation:
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Deportment of Obstetrics and Gynecology, Sunnybrook and Women's College Health Sciences Center, University of Toronto, Ontario, Canada. jodi.shapiro@utoronto.ca |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anthropometry
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methods* Cervix Uteri / ultrasonography* Female Gestational Age Humans Likelihood Functions Obstetric Labor, Premature / etiology, ultrasonography* Predictive Value of Tests Pregnancy Retrospective Studies Risk Factors Time Factors Twins* Ultrasonography, Prenatal / methods*, standards* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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