| Cervical glandular atypia associated with squamous intraepithelial neoplasia: a premalignant lesion? | |
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MedLine Citation:
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PMID: 3950029 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Recent studies have described premalignant changes in the endocervical epithelium, but morphological criteria for the diagnosis of cervical glandular atypia of lesser severity than adenocarcinoma in situ have not been established. Adenocarcinoma in situ is often associated with cervical intraepithelial neoplasia (CIN). The endocervical mucosa in 105 cases of CIN grade III was evaluated and compared with that of 100 controls. Sixteen cases of cervical glandular atypia and one case of adenocarcinoma in situ were identified, and it was possible to discriminate between these and a range of benign glandular lesions. Interestingly, the control series included two patients with cervical glandular atypia, one of whom on review had had a cone biopsy for CIN. The progression of cervical glandular atypia through adenocarcinoma in situ to invasive adenocarcinoma is known, but the natural history of cervical glandular atypia is as yet uncertain. |
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Authors:
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L J Brown; M Wells |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical pathology Volume: 39 ISSN: 0021-9746 ISO Abbreviation: J. Clin. Pathol. Publication Date: 1986 Jan |
Date Detail:
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Created Date: 1986-04-11 Completed Date: 1986-04-11 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0376601 Medline TA: J Clin Pathol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 22-8 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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pathology Adult Aged Carcinoma in Situ / pathology Cell Transformation, Neoplastic Cervix Uteri / pathology Female Humans Middle Aged Mitosis Precancerous Conditions / pathology* Uterine Cervical Neoplasms / pathology* |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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