| Cervical follicular dendritic cell sarcoma: a case report and review of the literature. | |
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MedLine Citation:
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PMID: 21658332 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Follicular dendritic cell (FDC) sarcoma is a rare tumour with a low-to-intermediate grade of malignancy. It frequently occurs in cervical, mediastinal and axillary lymph nodes. In approximately 30% of cases an extranodal localization has been reported (tonsils, oral cavity, mediastinum, liver, and spleen). Very little is known about possible treatment options and overall prognosis. This case reports a 66 year-old patient, who underwent surgical removal of a persistently enlarged right cervical lymph node. The histopathological examination revealed a spindle cell tumour with lymphocyte and plasma cell infiltrates. Neoplastic cells stained positive for CD21, CD23 and CD35, thus confirming the diagnosis of FDC sarcoma. The neoplasm recurred two years later and partial regression was achieved by IGEV rescue therapy. We briefly discuss clinical history, histopathological differential diagnosis and treatment options of FDC sarcoma. |
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Authors:
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M Pizzi; K Ludwig; G Palazzolo; G Busatto; C Rettore; G Altavilla |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of immunopathology and pharmacology Volume: 24 ISSN: 0394-6320 ISO Abbreviation: Int J Immunopathol Pharmacol Publication Date: 2011 Apr-Jun |
Date Detail:
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Created Date: 2011-06-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8911335 Medline TA: Int J Immunopathol Pharmacol Country: Italy |
Other Details:
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Languages: eng Pagination: 539-44 Citation Subset: IM |
Affiliation:
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Department of Diagnostic Medical Sciences and Special Therapies University of Padova, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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